Psychoanalysis as Science
AbstractPsychoanalysis is one of the most prominent and most intensely discussed research programs of the twentieth century. One important debate in the philosophy of medicine centers around the...
View ArticleEffectiveness of Software-Based Hardening for Radiation-Induced Soft Errors...
AbstractFor decades, radiation-induced failures have been a known issue for aero-space systems, in which redundancy mechanisms are employed as a protection method. Due to the shrinking of structures...
View ArticleJournalismus: Die neuen Nachrichtenkonkurrenten im Netz
ZusammenfassungAnderswo wird gerade der Journalismus neu erfunden – hierzulande wartet man lieber noch ein bisschen ab. Wir zeigen sechs große Trends der nächsten Jahre.
View ArticleThe frequency of cartilage lesions in non-injured knees with symptomatic...
AbstractIntroductionAre symptomatic tear injuries to the menisci of the knee frequently or always associated with cartilage damage to the corresponding articular surfaces and other joint surfaces,...
View ArticleDependability Aspects in Configurable Embedded Operating Systems
AbstractAs all conceptual layers in the software stack depend on the operating system (OS) to reliably provide resource-management services and isolation, it can be considered the “reliable computing...
View ArticleDevelopment and Implementation of a Rotating Nanoimprint Lithography Tool for...
AbstractUniform molding and demolding of structures on highly curved surfaces through conformal contact is a crucial yet often-overlooked aspect of nanoimprint lithography (NIL). This study describes...
View ArticleProphylaxen
ZusammenfassungDie Pneumonieprophylaxe bei beatmeten Patienten zur Vermeidung einer Ventilator-assoziierten Pneumonie (VAP) ist auf Grund einer deutlich erhöhten Morbidität und Letalität von...
View ArticleDevelopment of an individual helmet orthosis for infants based on a 3D scan
AbstractAn early childhood skull deformity can have long-term health and aesthetic consequences for the growing toddler. Individual helmet therapy aims at a healthy growth of the skull shape, although...
View ArticleDisseminated tumour cells with highly aberrant genomes are linked to poor...
AbstractBackground:Chromosomal instability (CIN) has repeatedly been identified as a prognostic marker. Here we evaluated the percentage of aberrant genome per cell (PAG) as a measure of CIN in single...
View ArticleResponse-adapted lenalidomide maintenance in newly diagnosed myeloma: results...
AbstractThe MM5 trial aimed at demonstrating a progression-free survival (PFS) difference in continued vs. response-adapted (in case of complete response, CR) lenalidomide (LEN) maintenance therapy...
View ArticleLenalidomide versus bortezomib maintenance after frontline autologous stem...
AbstractLenalidomide (LEN) maintenance (MT) post autologous stem cell transplantation (ASCT) is standard of care in newly diagnosed multiple myeloma (MM) but has not been compared to other agents in...
View ArticleBortezomib-based induction, high-dose melphalan and lenalidomide maintenance...
AbstractIntensive upfront therapy in newly-diagnosed multiple myeloma (MM) including induction therapy (IT), high-dose melphalan (MEL200), and autologous blood stem cell transplantation (ASCT) followed...
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A force-compensated compliant MEMS-amplifier with electrostatic anti-springs
AbstractIn this paper, an electrostatic compliant mechanical amplifier intended for force-compensated displacement amplification in MEMS sensor applications is described. Usually, mechanical...
View ArticleGenetic alterations driving metastatic colony formation are acquired outside...
AbstractMouse models indicate that metastatic dissemination occurs extremely early; however, the timing in human cancers is unknown. We therefore determined the time point of metastatic seeding...
View ArticleStochastic system identification without an a priori chosen kinetic...
AbstractKinetic models are at the heart of system identification. A priori chosen rate functions may, however, be unfitting or too restrictive for complex or previously unanticipated regulation. We...
View ArticleTunable 3D/2D magnetism in the (MnBi2Te4)(Bi2Te3)m topological insulators family
AbstractFeasibility of many emergent phenomena that intrinsic magnetic topological insulators (TIs) may host depends crucially on our ability to engineer and efficiently tune their electronic and...
View ArticleInterleukin-6 trans-signaling is a candidate mechanism to drive progression...
AbstractAlthough thousands of breast cancer cells disseminate and home to bone marrow until primary surgery, usually less than a handful will succeed in establishing manifest metastases months to years...
View ArticleThe Scientific Calibration of the Dawn Framing Camera
AbstractNASA’s Dawn mission visited the large main-belt asteroids Ceres and Vesta, returning a rich data set. Its science and navigation cameras, Framing Cameras 1 and 2, provided more than 100,000...
View ArticleRituximab, gemcitabine and oxaliplatin in relapsed or refractory indolent and...
AbstractRituximab, gemcitabine and oxaliplatin (R-GemOx) has demonstrated to be effective and safe in lymphoma patients. We aimed to determine the maximum tolerated dose (MTD) of oxaliplatin in...
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